The science behind GloNua

Our Mission

GloNua: Empowering Better Health for Body and Mind

At GloNua, we believe that lasting health is about more than simply managing energy, weight or avoiding illness. It is about creating the foundations for energy, resilience, vitality and long-term wellbeing — supporting people to live healthier, more balanced and fulfilling lives.

Our approach brings together evidence-informed nutrition, physical activity, healthy lifestyle habits, mindfulness, recovery and responsible supplementation to help individuals make positive, sustainable changes. We are passionate about sharing knowledge and practical guidance that empowers people to take greater ownership of their health and make informed choices that work for their individual needs.

Nutrition, Movement and Lifestyle

Nutrition and physical activity remain fundamental pillars of lifelong health. A balanced, nutrient-dense diet provides the body with the essential building blocks it needs to function, repair and thrive, while regular movement supports cardiovascular health, strength, mobility, metabolic health and mental wellbeing.

Exercise does not have to mean intense gym sessions. Walking, resistance training, cycling, swimming, yoga, sport and everyday movement can all contribute to a healthier, stronger and more active life. The key is finding sustainable activities that can become part of everyday living.

We also recognise that modern wellness extends beyond food and exercise. Sleep, stress management, recovery, social connection and time spent in nature all play an important role in how we feel and function. Getting outdoors, walking in nature or simply taking time away from an increasingly digital and sedentary lifestyle can support mental wellbeing, reduce stress and help restore balance.

A More Complete Approach to Wellness

At GloNua, our aim is to bring these elements together through science-led education, health and wellness consultancy, nutritional guidance and carefully considered supplementation. Supplements can have a valuable role in supporting nutritional needs, but they should complement — rather than replace — a balanced diet, regular movement, adequate sleep and other healthy lifestyle foundations.

Our philosophy is centred on informed choice rather than quick fixes. We believe that understanding your body, your nutrition and your lifestyle is an important first step towards making meaningful and sustainable improvements.

GloNua is about empowering people to invest in their health — building healthier habits today to support greater vitality, resilience and quality of life for years to come.

Better nutrition. More movement. Greater balance. A healthier life.

It's what's inside
that counts.

Adopting a nutrient dense diet based on thousands of years of evolution and genetic modelling can significantly enhance your health. By focusing on whole, less processed foods like Meats, vegetables, healthy fats and other proteins ignite your metabolic system increase overall health and reduce the risk of chronic diseases. This approach promotes sustained energy, better digestion, better mood and cognition, mental energy and positive mindset with a healthier body & mind.

THE SCIENCE BEHIND THE LIFESTYLE

Click on the links below for more interesting reading.

β-Hydroxybutyrate as an epigenetic modifier: Underlying mechanisms and implications

https://www.cell.com/heliyon/fulltext/S2405-8440(23)08306-8?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2405844023083068%3Fshowall%3Dtrue

Levels of most cardiometabolic outcomes decreased linearly with the decrease in carbohydrate intake.

https://pubmed.ncbi.nlm.nih.gov/35537861/

https://www.mdpi.com/1422-0067/23/23/14564

Beneficial Effects of Exogenous Ketogenic Supplements on Aging Processes and Age-Related Neurodegenerative Diseases:

https://www.mdpi.com/2072-6643/13/7/2197/htm

https://pubmed.ncbi.nlm.nih.gov/33637354/

ketone monoester supplementation improves cerebral blood flow and cognition in obesity: A randomized cross-over trial

https://physoc.onlinelibrary.wiley.com/doi/10.1113/JP281988

The Role of β-hydroxybutyrate, its polymer poly-β-hydroxybutyrate and inorganic polyphosphate in mammalian health and disease

Weight loss, improved physical performance, cognitive function, eating behavior, and metabolic profile in a 12-week ketogenic diet in obese adults

Ohio State University 2018 Keto Conferance. Emerging Science of Nutritional Ketosis. 

Stubbs, B.Cox, P.; Evans, R.; Santer, P.; Miller, J.; Faull, O.; Magor-Elliott, S.; Hiyama, S.; Stirling, M.; Clarke, K. (2017). On the metabolism of exogenous ketones in humans. Front. Physiol.

Cox, P.J., Kirk, T., Ashmore, T., Willerton, K., Evans, R., Smith, A., Murray, Andrew J., Stubbs, B., West, J., McLure, Stewart W., et al. (2016). Nutritional Ketosis Alters Fuel Preference and Thereby Endurance Performance in Athletes. Cell Metabolism 24, 1-13.

https://www.physiology.org/doi/abs/10.1152/ajpendo.1992.262.5.e631

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7436967/

β-Hydroxybutyrate: A signaling metabolite in starvation response?Rojas-Morales P, Tapia E, Pedraza-Chaverri J.Cell Signal. 2016 Aug;28(8):917-23. doi: 10.1016/j.cellsig.2016.04.005. Epub 2016 Apr 13.PMID: 27083590

From bedside to battlefield: intersection of ketone body mechanisms in geroscience with military resilience https://link.springer.com/article/10.1007/s11357-020-00277-y

https://www.nih.gov/news-events/nih-research-matters/brown-fat-associated-less-heart-metabolic-disease

Review.

Body composition changes in physically active individuals consuming ketogenic diets https://jissn.biomedcentral.com/articles/10.1186/s12970-021-00440-6

Ketone bodies as signaling metabolites.Newman JC, Verdin E.Trends Endocrinol Metab. 2014 Jan;25(1):42-52. doi: 10.1016/j.tem.2013.09.002. Epub 2013 Oct 18.PMID: 24140022 Free PMC article.

Review.

β-hydroxybutyrate: much more than a metabolite.Newman JC, Verdin E.Diabetes Res Clin Pract. 2014 Nov;106(2):173-81. doi: 10.1016/j.diabres.2014.08.009. Epub 2014 Aug 19.PMID: 25193333 Free PMC article. Review.

The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.Youm YH, Nguyen KY, Grant RW, Goldberg EL, Bodogai M, Kim D, D'Agostino D, Planavsky N, Lupfer C, Kanneganti TD, Kang S, Horvath TL, Fahmy TM, Crawford PA, Biragyn A, Alnemri E, Dixit VD.Nat Med. 2015 Mar;21(3):263-9. doi: 10.1038/nm.3804. Epub 2015 Feb 16.PMID: 25686106 Free PMC article.

The Ketone Body, β-Hydroxybutyrate Stimulates the Autophagic Flux and Prevents Neuronal Death Induced by Glucose Deprivation in Cortical Cultured Neurons.Camberos-Luna L, Gerónimo-Olvera C, Montiel T, Rincon-Heredia R, Massieu L.Neurochem Res. 2016 Mar;41(3):600-9. doi: 10.1007/s11064-015-1700-4. Epub 2015 Aug 25.PMID: 26303508

Effects of Ketone Bodies on Brain Metabolism and Function in Neurodegenerative Diseases.Jensen NJ, Wodschow HZ, Nilsson M, Rungby J.Int J Mol Sci. 2020 Nov 20;21(22):8767. doi: 10.3390/ijms21228767.PMID: 33233502 Free PMC article. Review.

Understanding Dietary Intervention-Mediated Epigenetic Modifications in Metabolic Diseases.Asif S, Morrow NM, Mulvihill EE, Kim KH.Front Genet. 2020 Oct 15;11:590369. doi: 10.3389/fgene.2020.590369. eCollection 2020.PMID: 33193730 Free PMC article.

Review.

Beta-Hydroxybutyrate Enhances BDNF Expression by Increasing H3K4me3 and Decreasing H2AK119ub in Hippocampal Neurons.Hu E, Du H, Shang S, Zhang Y, Lu X.Front Neurosci. 2020 Oct 28;14:591177. doi: 10.3389/fnins.2020.591177. eCollection 2020.PMID: 33192276 Free PMC article.

Epigallocatechin Gallate Effectively Affects Senescence and Anti-SASP via SIRT3 in 3T3-L1 Preadipocytes in Comparison with Other Bioactive Substances.Lilja S, Oldenburg J, Pointner A, Dewald L, Lerch M, Hippe B, Switzeny O, Haslberger A.Oxid Med Cell Longev. 2020 Oct 21;2020:4793125. doi: 10.1155/2020/4793125. eCollection 2020.PMID: 33149809 Free PMC article.

https://ketonutrition.org/ketones-and-nafld/

Effects of β-hydroxybutyrate on cognition in patients with type 2 diabetes

https://eje.bioscientifica.com/view/journals/eje/aop/eje-19-0710/eje-19-0710.xml

Veech RL, Bradshaw PC, Clarke K, Curtis W, Pawlosky R, King MT. Ketone bodies mimic the life span extending properties of caloric restriction. IUBMB Life. 2017;69(5):305-314

Holdsworth, D.A., Cox, P.J., Kirk, T., Stradling, H., Impey, S.G., and Clarke, K. (2017). A Ketone Ester Drink Increases Postexercise Muscle Glycogen Synthesis in Humans. Med Sci Sports Exerc.

Vandoorne, T., De Smet, S., Ramaekers, M., Van Thienen, R., De Bock, K., Clarke, K., and Hespel, P. (2017). Intake of a Ketone Ester Drink during Recovery from Exercise Promotes mTORC1 Signaling but Not Glycogen Resynthesis in Human Muscle. Front. Physiol. 8, 310.

Sato, K., Kashiw.aya, Y., Keon, C.A., Tsuchiya, N., King, M.T., Radda, G.K., Chance, B., Clarke, K., and Veech, RL. (1995). Insulin, ketone bodies, and mitochondrial energy transduction. FASEB J. 9, 651-658.

Cahill, G.F., Jr. (1970). Starvation in man. New Engl J Med 282, 668-675.

Ohio State University 2018 Keto Conferance. Emerging Science of Nutritional Ketosis. 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC507673/

https://www.cell.com/cell-metabolism/fulltext/S1550-4131(19)30611-4

https://ncbi.nlm.nih.gov/pubmed/31820376

https://ncbi.nlm.nih.gov/pubmed/28398950

https://sciencedirect.com/science/article/pii/S1550413116304387

https://ncbi.nlm.nih.gov/pubmed/28588499

https://frontiersin.org/articles/10.3389/fphys.2017.00806/full…

https://ncbi.nlm.nih.gov/pubmed/28599043

https://ncbi.nlm.nih.gov/pubmed/31730565

ENHANCE YOUR METABOLIC SYSTEM TODAY

A reduced carbohydrate diet is a better approach for numerous health outcomes and leads to an enhanced you. By adding Goketo  BhB or MCT you can really feel the difference in your everyday life, cognition, recreation / workouts. GloNua ranges are formulated with 100% pure BhB Ketones and MCT C8 coconut powder given you a superior dietary supplement advantage.